INTRODUCTION Diabetes mellitus is a common chronic disease in which the blood sugar level of an individual is high
Diabetes mellitus is a common chronic disease in which the blood sugar level of an individual is high. It can be due to the lack of production and/or action of insulin, a sedentary lifestyle or it can also be hereditary. The most common type of diabetes is type 2 diabetes. As reported by Rafael R. Castillo of Philippine Daily Inquirer, Philippines is considered as one of the “hot spots” in the Western Pacific Region and ranks fifth behind China, Indonesia, Japan, and Thailand in the number of diabetics. The number of patients with diabetes is increasing annually, with several millions of individuals diagnosed to have diabetes. According to the Department of Health, diabetes is one of the leading causes of death in the Philippines.
If diabetes is left untreated, it can cause serious health problems to the individual with the said disease. The most common complications it provides include cardiovascular diseases, kidney diseases, eye diseases, nerve damage and complications within the feet that can lead to amputation.
Some medications are expensive, and it was noted in a FASID (Foundation for Advanced Studies on International Development) report that the Philippines had one of the highest medicine prices in Asia. Plus, different kinds of medicine cause different side effects including stomach pain, nausea, bloating, diarrhea and some may cause serious conditions. (Dansinger, M., 2017).
There are some plants with hypoglycemic effects that can be found in the locality. Phytoconstituents like flavonoids, phenolics, terpenoids, alkaloids, polyphenols, tannins, coumarins, anthraquinones, saponins, carbohydrates, cardiac glycosides, and minerals help reduce blood sugar level (Yatoo, M.I., Gopalakrishna, A., Algawany, M., Dhama, K., 2016).
Because of the aforementioned reasons, this study aims to investigate the possible antidiabetic activity of Cocos nucifera l., and to find a cheaper and safer alternative for treating one of the most common chronic diseases in the world.
MATERIALS AND METHODS
A. Collection and Preparation of Cocos nucifera L. meat
The coconuts were collected locally at P-4 Malvar street, Poblacion, Nabunturan, Compostela Valley and were then sun-dried for 10 days. The dried meats of the coconuts were chopped into fined pieces and further ground.
B. Soaking and Extraction of Coconut meat
At 1:2 ratio (1-part coconut meat, 2-part ethanol), the coconut meats were soaked in 95% ethanol for 3 days. The soaked samples were then extracted using the oil bath method.
C. Testing of Antidiabetic Activity
The samples were then sent to a laboratory for the testing of the antidiabetic activity of the coconut meat extract.
D. Data Analysis
One-way ANOVA will be used as the statistical tool.